Methyl Bromide IND

Overview

Methyl Bromide IND

Methyl Bromide, a colorless and odorless gas, is widely used as a chemical intermediate in pharmaceutical, agricultural, and industrial applications. Derived from pure bromine sourced from the Dead Sea, its use is regulated under the Montreal Protocol due to its environmental impact, necessitating careful product stewardship.

Formula: CH3Br

Chemical Properties

CAS Number: 74-83-9

Chemical Properties

Appearance: Colorless, odorless gas

Chemical Properties

Density: 1.354 g/mL

Chemical Properties

Specific Gravity: 1.73-1.735 at 0°C

Chemical Properties

Distillation Range: 3.5-5°C at 760 mm Hg

Chemical Properties

Acidity (as HBr): Less than 6 ppm

Chemical Properties

Packaging Options

Returnable Cylinders

50 kg and 100 kg

Steel Cylinders

675 kg

Key Benefits

Versatile Applications

Suitable for use in pharmaceuticals, agrochemicals, and industrial products.

Chemical Intermediate

Used in various chemical synthesis processes.

Applications

Pharmaceuticals

Used as an intermediate in the synthesis of active pharmaceutical ingredients (APIs).

Agriculture

Employed as a fumigant for soil and post-harvest pest control.

Industrial

Acts as a methylating agent in various industrial chemical processes.

Safety and Handling

Regulatory Compliance

Listed under the Montreal Protocol, requiring stringent controls to prevent environmental release.

Storage

Store in specialized containers and isotanks designed for safe handling and transport.

Regulatory Considerations

Montreal Protocol: Methyl Bromide is controlled under this international treaty aimed at phasing out substances that deplete the ozone layer. Users must adhere to strict guidelines and regulations to mitigate environmental impact.

Uses of Methyl Bromide (IND) in
the Pharmaceutical Industry

These applications highlight the critical role of Methyl Bromide in the pharmaceutical industry, making it an indispensable chemical in the development and production of a wide range of medicinal products.

Intermediate in Drug Synthesis

Methyl Bromide serves as a crucial intermediate in the synthesis of various pharmaceutical compounds. Its ability to introduce methyl groups into molecules is vital for the development of numerous drugs.

Alkylating Agent

It acts as a powerful alkylating agent, used to modify chemical structures during the synthesis of active pharmaceutical ingredients (APIs). This modification is essential for the biological activity and effectiveness of many drugs.

Production of APIs

Utilized in the production of specific APIs, Methyl Bromide is essential for creating drugs that target a variety of medical conditions, including pain relief, sedation, and anticonvulsant medications.

Chemical Reagent

As a versatile chemical reagent, it facilitates numerous organic reactions in pharmaceutical research and development. It helps in the creation of complex molecules that are foundational to new drug formulations.

Radiolabeled Pharmaceuticals

Methyl Bromide is employed in the synthesis of radiolabeled compounds used in diagnostic imaging and research. These compounds are crucial for tracking and studying the behavior of drugs within the body.

Precursor in Synthesis

Used as a precursor for synthesizing more complex brominated compounds, Methyl Bromide is essential for further chemical transformations needed in pharmaceutical manufacturing processes.

Solvent

Occasionally used as a solvent in specific pharmaceutical reactions, aiding in the dissolution and reaction of various chemical compounds during drug production.

Production of Antimicrobials

Involved in the synthesis of certain antimicrobial agents, contributing to the development of drugs that combat bacterial, viral, and fungal infections.