1-Bromopropane (n-Propylbromide)

Overview

1-Bromopropane (n-Propylbromide)

1-Bromopropane is a high-purity, transparent liquid produced using bromine sourced from the Dead Sea. It is widely applied as a chemical intermediate and industrial solvent, particularly in (vapor) degreasing of metal parts. A notable application of 1-Bromopropane is in producingvalproic acid for pharmaceutical use. Due to its hazardous nature, appropriate safety precautions are required when handling this product.

Appearance: Colorless liquid

Typical Properties

Melting Point: -110°C

Typical Properties

Boiling Point: 71°C

Typical Properties

Density: 1.354 g/mL

Typical Properties

Vapor Pressure: 19.5 kPa (at 20°C)

Typical Properties

Oxidizing Properties: Non-oxidizing

Typical Properties

Hazards - Signal Word: Danger

Typical Properties

Flash Point: None (ASTM D 56)

Typical Properties

Solubility in Water: 2.5 g/L at 20°C

Typical Properties

Chemical Formula: C3H7Br

General Specifications

1-Bromopropane Assay (wt%): Min 99.5%

General Specifications

Appearance: Clear liquid

General Specifications

Color (APHA): Max 50

General Specifications

CAS Number: 106-94-5

General Specifications

Acidity as HCl (wt%): Max 0.003%

General Specifications

Isopropylbromide (ppm): Max 100

General Specifications

Evaporation Residue (ppm): Max 50

General Specifications

Packaging

1-Bromopropane is available in the following packaging options:

216L Steel Drum with Epoxy Coating

Net product weight: 250 kg, on a pallet of 4 drums.

Isocontainer (Bulk):

For larger quantities.

Key Benefits

High Purity Grade Product

Ensures superior performance in all applications.

Global Supply Chain

Guarantees reliable availability.

ISO Certified Production

Ensures consistent quality and reliability.

REACH and K-REACH Registered

Compliant with European Union and Korean regulations for chemical substances

Applications

Chemical Intermediate

Crucial in the synthesis of various compounds.

Industrial Solvent

Effective in vapor degreasing of metal parts.

Pharmaceuticals

Key in the production of valproic acid.

Uses of 1-Bromopropane (n-Propylbromide)
in the Pharmaceutical Industry

These uses and benefits highlight the significant role of 1-Bromopropane (n-Propylbromide) in the pharmaceutical industry, making it an indispensable chemical in drug development and manufacturing processes.

Intermediate in Drug Synthesis

Building Block: Acts as a crucial intermediate in synthesizing a variety of pharmaceutical compounds, facilitating the development of more complex molecules needed for new drugs.

Intermediate in Drug Synthesis

Versatile Reagent: Used to introduce bromine atoms into organic molecules, essential for creating many pharmaceuticals.

Alkylating Agent

Chemical Modification: Employed as an alkylating agent to introduce propyl groups into molecules, which is vital for modifying the chemical structure of drugs to enhance their biological activity and therapeutic effects.

API Production

Active Ingredient Synthesis: Utilized in the production of active pharmaceutical ingredients (APIs) for medications that treat a range of conditions, including pain, inflammation, and neurological disorders

Radiolabeled Compounds

Diagnostic and Research Tools: Used in the synthesis of radiolabeled pharmaceuticals, which are essential for diagnostic imaging and tracking the distribution and metabolism of drugs within the body.

Solvent

Chemical Reactions: Occasionally used as a solvent in pharmaceutical manufacturing processes, aiding in the dissolution and reaction of various chemical compounds.

Benefits of of 1-Bromopropane (n-Propylbromide)
in the Pharmaceutical Industry

High Reactivity

Efficient Synthesis: Its high reactivity allows for efficient synthesis of complex pharmaceutical compounds, reducing production times and increasing yields.

Versatility

Multiple Applications: Its use as both an intermediate and an alkylating agent makes it a versatile component in drug synthesis, suitable for a wide range of pharmaceutical applications.

Enhanced Drug Properties

Improved Efficacy: By introducing propyl groups into drug molecules, it helps improve the efficacy and potency of pharmaceutical products.

Enhanced Drug Properties

Stability and Bioavailability: Enhances the stability and bioavailability of active ingredients, leading to more effective medications.

Radiolabeling

Advanced Diagnostics: Enables the creation of radiolabeled compounds for advanced diagnostic techniques, crucial for medical imaging and research.

Cost-Effective Production

Economical Synthesis: Its efficient reactivity and versatility can lead to cost-effective production processes, lowering overall manufacturing costs for pharmaceutical companies.

Research and Development

Facilitates Innovation: Essential in pharmaceutical R&D, helping researchers develop novel drugs and therapeutic agents through innovative chemical transformations.